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Nicotinamide N-methyltransferase as a potential therapeutic target in metabolic and related diseases

Discontinue use and consult a healthcare provider if you experience: Severe allergic reactions (rash, difficulty breathing, swelling), persistent injection site infections, or any concerning symptoms that do not resolve

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[1] In practice, 1 mL (which provides the full 100 mg of B and B, etc.) is a common dose for general supplementation in deficient states, but clinicians may start with lower volumes for mild deficiencies or in smaller patients

Initial correction of significant deficiency typically involves weekly or biweekly injections for several weeks until levels normalize and symptoms resolve