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He J, Zhong Y, Li Y, Liu S, Pan X

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If outcomes seem favourable, apply the active-laced formula on your face (initially only 1 or 2 times a week)

TNF- can activate the apoptotic signaling pathway by targeting TNFR1 or activate downstream NF-B to induce the production of other cytokines by targeting TNFR2 (Sun and Kanwar, 2015)