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Rating: 4.0045 (19 reviews)

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Defects in this gene result in familial adenomatous polyposis (FAP), an autosomal dominant precancerous condition that often progresses to malignancy

The depletion of GPX4 can increase the sensitivity of hepatocytes or cardiomyocytes to lipid peroxides, which can accelerate IRI-induced liver or cardiac injury [246,247,248]

The amylin pathway represents a fundamentally different approach than GLP-1 agonists, making it complementary rather than redundant

Although oxidative stress was defined originally as a balance between oxidants and antioxidants systems, an equilibrium among antioxidant strategies is needed to avoid the generation of oxidants and ROS (Mari et al., 2010)