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Epifluorescence microscopy Epifluorescence microscopy was performed on Bb B31 strain using the same preparation as applied for the flow cytometry experiments

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The primary endpoint of the study was the number of treatment-related adverse events from baseline to the end of follow-up at 26 weeks, while the exploratory endpoints were changes in body weight, glycemic parameters, and various hormones

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Also the dualcentered network analysis for zymosan and M2like macrophages showed that IL4c application prevented the eosinophil depletioninduced collapse of the neighborhood architecture (Fig EV3)