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We generated an NCI-H446 xenograft mouse model to confirm these changes in vivo , and the results also showed altered levels of IL-6 and IL-1 (Fig

The modification of HMGB1, such as phosphorylation and acetylation, is vital for its translocation (25, 2932)

Mice were killed 1 h after the last dosing using CO 2 inhalation followed by cervical dislocation

[15,17] roGFPs are engineered to have two cysteine residues whose oxidation to form a disulfide induces structural changes that alter their fluorescence properties