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Patients often notice reduced ankle and leg puffiness within 4-8 weeks, correlating with initial weight-loss phases rather than medication dosage alone

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Unusually pale or yellow skin is often the result of underlying health conditions that vitamin B12 typically protects against, such as [4]: Vitamin deficiency anemias A B12 deficiency can result in blood conditions, like anemia, that are marked by a scarcity of healthy red blood cells