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Our study revealed that HK2-deficient cells also exhibited increased sensitivity to RDA and increased activation of caspases induced by TNF/5z7, when compared to WT cells (Supplementary Fig

Klotho The antiaging protein -Klotho is a 130 kDa membrane-bound protein mainly synthesized in the kidneys and acting as a coreceptor for FGF23, thereby mediating its renal effects with respect to phosphate handling and calcitriol synthesis [80]