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It's a critical consideration, and the answer affects your health journey with TRT

Results are typically available within a few days

However, those patients who are AMA negative and thought to nevertheless have PBC need radiographic demonstration of a normal biliary tree on cholangiography, either by magnetic resonance cholangiopancreatography (MRCP) or endoscopic retrograde cholangiopancreatography (ERCP), to exclude other possible diagnoses, particularly primary sclerosing cholangitis (PSC)

Additionally, sublingual B12 bypasses intestinal absorption issues, and is a more accessible treatment option for vitamin B12 deficiency