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Lymphatic targeting may be achieved via the delivery of macromolecular therapeutics (for example, proteins and peptides), small-molecule therapeutics in association with macromolecular carriers (for example, nanoparticles, polymers, liposomes and dendrimers) or small-molecule therapeutics that associate, in situ , with endogenous macromolecular constructs (for example, lipoproteins and proteins) or cells that are transported from interstitial tissues via lymphatic rather than blood capillaries

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Moreover, by combining spatiotemporal omics and big data models, the interaction between IgG and other aging hallmarks (such as chronic inflammation and stem cell depletion) can be analyzed to provide systematic solutions for delaying aging