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Rhein lysinate can also improve hepatic function through decreasing hepatic adipose infiltration and the expression of inflammatory factors in diabetic mouse model induced by STZ and diabetic food [109]

Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-alpha in the rat

Ferroptosis frequently occurs in the tubules during the progression of renal disease due to the vulnerability of renal tubules to oxidative stress and lipid peroxidation (130)