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Biochem J 300 (Part 1): 271276

UPDATE POST OF MTHFR BLOG MTHFR Gene Mutation-What's the Big Deal About Methylation

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The proof-of-principle results demonstrating that disruption of AHCY dimerization suppresses tumor growth further suggest that this strategy may complement traditional active-site inhibition and inspire analogous interventions for other metabolic enzymes with moonlighting regulatory functions in cancer