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Alternatively, the more supported hypothesis is that there could be hyper-responsivity of the cholinergic receptors at a hypothalamic level, causing a greater decrease in somatostatin tone, and elevated GH release from the anterior pituitary gland (153)

All above is consistent with anti-inflammatory effect of GIPR/GLP1R agonism, which plays a role in improving atherosclerosis lesion severity

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Biomedical science is becoming more aware of the critical role played by peptides in biological signaling