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Tissue sections were imaged under a microscope (DMi8, Leica Microsystems, Wetzlar, Germany, with a Hamamatsu Orca Flash 4 v3 sCMOS camera) where fluorescence was excited with a lumencor spectra X using 550 nm (secondary antibody Alexa Fluor 594), 470 nm (secondary antibody Alexa Fluor 488) or 385 nm (DAPI), and exposure time was held constant for each color channel regarding magnification and staining

Tested to the highest standard

V ss , volume of distribution (steady state)

As a triple monoamine reuptake inhibitor, Tesofensine serves as a valuable research tool for investigating neuropharmacology, appetite control, energy balance, and metabolic signaling in controlled laboratory environments

Drugs such as statins and metformin are context-specific