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The goal is to obtain optimum fitness in each of these, since theyve been shown to form a powerful shield against our biggest health threats: cardiovascular disease, cancer, metabolic dysfunction, and degenerative neurological disorderswhat Attia refers to as the four horsemen. Fitness sounded like good medicine to me, but the emphasis on exercise also prompted a lot of questions: What kind

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Red cells have a much higher concentration of folate than the serum, so measuring folate on a haemolysed sample would tell you nothing

There is, however, direct evidence for a regulatory role of amino-acids on IGF-I production that is independent of insulin