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Methods Enzymol Basel Verlag Chemie 1983;3:258-65

Histone reductions occur in response to factors inducing cell senescence If histones were indeed reduced in irradiated cells that became senescent, then it would stand to reason that such reductions would also be expected to accompany cellular senescence triggered by other stimuli

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Toxicol Ind Health 2020;36:8006

Although individual peptides have been investigated in various controlled studies, clinical data on the combined blend is limited, and further human trials are needed to establish efficacy and optimal dosing protocols