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Description

PMID 7559527

doi: 10.1126/science.1078540

Thus, we consider that together with other clinical variables and biomarkers, global MFIS and its domains constitute a diagnostic and prognostic aid in clinical practice for the design of personalized therapeutic strategies

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Multicollinearity issues/too many overlapping covariates : In this work, we start with a large number of covariates (300+) and many covariates overlap i.e