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reported that avicularin can exert a protective effect against ALF by activating the classic Nrf2/HMOX1/glutathione peroxidase 4 (GPX4) antioxidant stress pathway[3]

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In vitro experiments with RAW 264.7 cells, PCA was shown to inhibit the expression of TNF- by modulating the activation of the NF-B and MAPK pathways (Min et al., 2010)