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In situ hybridisation of AR mRNA expression in the mouse olfactory bulb showed a similar pattern of expression (Allen Brain Atlas, ISH Coronal image 4)

So, its recommended you take it daily for at least 12 weeks

In summary, cerebral MMA retention disrupts mitochondrial energy homeostasis, exacerbates oxidative stress, and triggers neuroinflammation and excitotoxicity, collectively driving neuronal death and CNS dysfunction