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These fish exhibit slower swim speed, weaker muscle strength, reduced muscle fiber diameters, and, in cases of LMNA (A539V) and LMNA (E358K), elevated heartbeats

We have previously shown that in some storage vesicles, LPL adopts a filament-like structure that follows the vesicle membrane and resembles the helical oligomer of LPL we solved by cryoEM 5

Nucleotide distribution and diversity of the initial/unselected DNA library Compared to RNA oligonucleotides, ssDNA oligonucleotides exhibit greater stability for long-term storage, notably due to their inherent resistance to enzymatic degradation by nucleases