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Furthermore, these findings support the potential application of metabolites, such as cystine, as adjuvants to improve the efficacy of existing antibiotics, which opens a new avenue for addressing clinical antibiotic resistance

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In animal studies, AOD-9604 reduced body weight gain by over 50% in obese mice during a 19-day treatment period, and significantly increased fat oxidation all without affecting insulin sensitivity or glucose regulation.[1,3] A randomized controlled trial in humans found that participants taking 1 mg of AOD-9604 daily lost an average of 2.8 kg (~6 lbs) over 23 weeks, compared to 0.8 kg (~1.7 lbs) in the placebo group

[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Potter N.A., Meltzer G.Y., Avenbuan O.N., Raja A., Zelikoff J.T