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Ipamorelin and CJC-1295 Complementary Research Mechanisms The research interest in studying Ipamorelin and CJC-1295 together stems from the complementary nature of their receptor mechanisms

Additionally, there are other medications that may exacerbate OSA and theoretically worsen daytime sleepiness, such as: Benzodiazepine receptor agonists Barbiturates Antiepileptic medications Sedating antidepressants such as mirtazapine (antidepressants can cause weight gain, which worsens sleep apnea due to obesity) Antihistamines Opiates Various medications have been studied for treating obstructive sleep apnea, including drugs that stimulate the respiratory system (directly like theophylline, or indirectly like acetazolamide), drugs that reduce risk of upper airway collapse (desipramine), antimuscarinic drugs (oxybutynin), and noradrenergic drugs (atomoxetine), but none of them have yet shown a significant ability to reduce OSA

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue with selective ghrelin receptor (GHSR) affinity

I.KhakuS.et al