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doi: 10.1136/jmedgenet-2012-101175 143 LinY

Viruses 13 (10), 2017

Potential risks and contraindications Given the limited understanding of DSIPs mechanisms and effects in humans, certain risks and contraindications must be taken into consideration: Unknown long-term effects : The long-term safety of DSIP has not been well-established, and the potential risks associated with chronic use remain unclear

Past performance is not indicative of future results

CAR-NK cell therapy, on the other hand, offers an advantage as it can be administered to an HLA-mismatched patient, and Phase I clinical trial is showing promising preliminary results (NCT03383978) (308)