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At 6 weeks post-operation, better graft incorporation at the tibial tunnel was observed in the 0.3 mg/ml GHK-Cu group, though this difference did not reach statistical significance

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The active ingredient, semaglutide, was approved by the FDA in 2021 for chronic weight management in adults and children 12 and older with obesity and for adults who are overweight with one or more weight-related health conditions, like type 2 diabetes or high blood pressure

The therapeutic mechanism may be associated with accelerated granulation tissue formation, reepithelialization, dermal remodeling, and collagen deposition through ERK1/2 signaling pathway