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Rare mutations in the SLC22A5 gene can cause a genetic condition called primary carnitine deficiency, which is usually discovered in infancy because it affects brain function, muscle function, and blood glucose levels

The long-term safety of repeated glutathione injections for skin lightening purposes is not fully established

However, these drugs are very expensive, have not been shown to prevent colectomy in severe ulcerative colitis (Aratari 2008), and may cause autoimmune diseases, cancer, infections, and viral reactivation syndromes including shingles (Colombel 2004)

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Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas