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Within the tumor microenvironment (TME), the specific ligand hepatocyte growth factor (HGF) is predominantly released by fibroblasts associated with cancer [1]

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Reported Side Effects & Research Safety Considerations Research safety data on Semax remains limited compared to more extensively studied compounds, with most available findings drawn from animal studies rather than large-scale human trials

However, the primary endpoints, defined as buprenorphine overall and peak exposures (measured by C max and AUC 028 days ), were objective measures that may be less impacted by potential bias compared with other safety or efficacy assessments

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