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2012;2012(3): CD001447

The resulting linkage is an isoxazole, which is hydrolytically stable and shows similar isosteric character of amide and ester bonds

S., Vanharanta, S., Obenauf, A

In the presence of environmental toxins, gut microbiota-derived metabolites (such as glycochenodeoxycholate) can induce ferroptosis, lipid metabolic disorders, and inflammation by activating the TFR and ACSL4 [83]