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Based on the scientific evidence available for mitochondria-relevant nutraceuticals, this article presents examples of frequent medical conditions, which require protective measures targeted on mitochondria as a holistic approach following advanced concepts of predictive, preventive, and personalized medicine (PPPM/3PM) in primary and secondary care

Some examples of these elements are calcium, which is necessary for building bones and for intracellular communication, iron, which is necessary for building a number of proteins (including haemoglobin, which is vital for transporting oxygen and, by extension, for cellular respiration), and folic acid, which is essential for "one-carbon metabolism," the building block of the nucleic acids needed for cell replication (Mousa, Naqash, & Lim, 2019)

In Phase 2 detoxification, various enzymes act directly on the toxic substances partially degraded and processed in Phase 1, such as heavy metals and organo-toxins, by binding them with protective compounds, thereby either inactivating the toxins

10.3390/antiox9080768 13