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An overproduction of inhibitory neurotransmitters and an underproduction of excitatory neurotransmitters can impair intestinal motility, leading to constipation (Figures 2D, E)

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The KruskalWallis rank sum test was used to assess overall differences among the two bumetanide groups and control group

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Landry et al., 2021b), due to H 2 S toxicity accumulation and respiratory chain dysfunction (Kanemaru et al., 2024)