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Summary scores of the Bayley-III cognitive, language and motor subscales at 6 and 12 months of age will be the primary outcome in the current study, while the assessment at 24 months will serve as secondary outcome

Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc 1 -cytochrome c oxidase supercomplex

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In the major trials, appetite changes appeared within the first weeks and measurable weight loss within the first two to three months, but the curves did not flatten until roughly month 12 to 18