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The anti-PD-1 antibody (RMP1-14, at a dosage of 5 mg per kg of body weight) or IgG (at a dosage of 10 mg per kg of body weight) was administered intraperitoneally three times per week over a duration of three weeks

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In contrast, HO activity is largely unaffected by protoporphyrins with nickel (Ni), copper (Cu), and magnesium (Mg) as central atoms (Drummond and Kappas, 1981)