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Souza RO, Miranda VC, Quintanilha MF, Gallotti B, Oliveira SRM, Silva JL, et al

ERAP1 gene polymorphism results in variation of its enzymatic function in the ER that leads to production of oligomeric peptides with low affinity to bind to disease associated HLA-B27 subtypes (and HLA-B40) in the ER-derived cytoplasmic vesicles

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