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S -bacillithiolation of the OhrR repressor occurs at its lone Cys15 residue leading to inactivation of OhrR and expression of the thiol-dependent OhrA peroxiredoxin for detoxification of organic hydroperoxides and NaOCl (Fuangthong et al., 2001

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This novel finding opens up promising avenues for the development of targeted therapies for specific GST-related diseases and sets the stage for the creation of more potent GST inhibitors

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