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O 2 is detoxified by superoxide dismutase (SOD) enzymes, which convert it into H 2 O 2

1 Introduction Despite several efforts towards exploring the origination and developing various therapeutic modalities, cancer has emerged as one of the most dreadful metabolic diseases globally, second to cardiovascular diseases, accounting for millions of recorded cases every year (Siegel et al., 2023)

Inhibition of GLS1 by BPTES improves glycolysis and oxidative phosphorylation (OXPHOS) in SS-like CD4 + T cells and thus slows the progression of SS (98) ( Table 1 )

Neonatal-onset propionic acidemia: neurologic and developmental profiles, and implications for management

1.15.1.1) is a metalloenzyme, catalyzing superoxide anion dismutation to H 2 O 2 and molecular oxygen, as shown in reaction 1 (Singh et al., 2017)