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Description

BRD4 is a member of the BET family with two BDs (BD1 and BD2) reading acetylated RelA, ERG, Twist, and Snail

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This is validated clinical data

J., Sendtner, M

As we have documented the tolerability of L-PAM+BSO when supported by autologous stem cell infusion in heavily pretreated relapsed and/or refractory neuroblastoma patients (NANT phase I study, NCT00005835, www.clinicaltrials.gov), using myeloablative L-PAM+BSO is clinically feasible