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In particular, huC242-SPDB-DM4 (IMGN242) is a novel ADC comprised of huC242 antibody conjugated to the potent maytansinoid via the cleavable disulfide-linker, which allows targeted delivery to pancreatic tumor cells and releases the potent maytansinoid in tumor cells

REDEFINE 4 an 84-week head-to-head efficacy and safety phase 3 trial of once-weekly CagriSema versus once-weekly tirzepatide

CD36 palmitoylation is important in lipid metabolism disorders, mitochondrial dysfunction, and inflammatory activation in MASH ( Table 3 ) ( Figure 5 )

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