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Leptin interferes with the insulin signaling pathway, leading to impaired glucose and lipid metabolism, and promotes liver fat accumulation, which is characteristic of MASLD [213, 214]

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Proc Natl Acad Sci U S A 102:11722, PMID: 15618409 Qanungo S, Starke DW, Pai HV, Mieyal JJ, Nieminen AL (2007) Glutathione supplementation potentiates hypoxic apoptosis by S -glutathionylation of p65-NFkappaB

Oxidative modifications of synovial proteins contribute to the formation of neo-antigens, triggering autoimmune responses [145]

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