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Oct 28 2015;114(8):1263-77

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Upon entering the cytoplasm, the chloride atoms on the drug are displaced by water molecule, resulting in a compound that binds to the N7 reactive center on purines and causes DNA damage

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The TME participates in tumorigenesis by generating a ROS niche through oxidative stress (OS) (Schiffer et al., 2018)

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30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development

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Negative cooperativity in ligand binding has long been known to be an intrinsic property for both IGF1R and IR

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