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Some patients with severe injuries may also require other intervention to ensure an optimal outcome (such as immobilization, splinting or surgery)

Studies involving humans show that mTBI, which may involve axonal damage or dysfunction as detected by diffusion tensor imaging, is associated with measurable decreases in CMRglc (Gross et al., 1996

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Notably, we observed increased fibrosis in Aldh1l2 KO mice at day 4 following caerulein treatment and a delay in the regeneration of acinar cells at day 7, consistent with a role for re-expression of ALDH1L2 in the recovery from pancreatic damage (Extended Data Fig

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