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Even in asthmatic patients who develop frequent comorbidities such as chronic rhinitis, sinusitis, atopic dermatitis, and certain food allergies, this Th2 cell-mediated inflammation is observed, given its prevalence in chronic allergic inflammation across multiple sites (Kay 2001)

It also exacerbates high blood pressure by damaging blood vessels, contributes to cardiomyopathy by altering heart function, and increases the risk of ischemia by obstructing coronary arteries