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J Alzheimers Dis 90:15011521 Hashim KNB, Matsuba Y, Takahashi M, Kamano N, Tooyama I, Saido TC, Hashimoto S (2024) Loss of glutathione elevates the A42/A40 ratio and the aggregation of the tau protein

Collectively, GGCT functions as a metabolic rheostat that orchestrates mitochondrial homeostasis through diverting Gln flux toward glutathione biosynthesis to fortify redox defense, while enhancing Glc-fueled TCA cycle anaplerosis to sustain cell proliferation

The expression of H 2 S in different tissues can jointly regulate the formation of fat

[3] The glycine cleavage system differs from the other complexes, and has a different nomenclature

Nature 448 , 474479 (2007)