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The relative abundance of Erysipelatoclostridium was increased in vehicle-treated mice that underwent the WD to LD switch (WD/LD-V) relative to the two control groups (LD/LD-V and WD/WD-V) but was not increased in 5A-1MQ-treated mice that underwent the same diet switch (WD/LD-T)

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As with any emerging pharmacological agent, the establishment of a safe and effective dosage for clinical use necessitates thorough and rigorous clinical trials