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Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, et al

3, 4, 5 However, it is the paracellular pathway, regulated by the tight junction (TJ), that is responsible for the greatest degree of apical cellcell adhesion, 6, 7 and which has received the most attention for its role in regulating mucosal permeability under normal and pathological conditions