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Mice have different metabolic rates, body composition, and adipose tissue biology than humans

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FIGURE 2 In contrast, with the administration of L-NAME, there was a moderate generalized irregularity in the diameter of blood vessels with moderate atrophy of the optic disc, faint presentation of the choroidal blood vessels appears immediately, and these lesions (Figure 2, IN, IIN) rapidly progress (Figure 3, AC

They understand that the medication works best as part of a comprehensive approach that includes nutrition, exercise, and behavioral changes