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Figure 1 illustrates mechanisms with APOE4 -related neurodegeneration linked to the diseases, adapted from Fernndez-Calle et al

FEMS Microbiol Lett 158:4550 Rivera-Lugo R, Light SH, Garelis NE, Portnoy DA (2022) RibU is an essential determinant of Listeria pathogenesis that mediates acquisition of FMN and FAD during intracellular growth

Gil-Campos M, Caete R, Gil A

*N0 is normally produced from L-arginine by nitric oxide synthase (NOS), which has been noted to be up-regulated in cells infected with vims that accesses cells through CD46, such as measles and HHV-6 type A (Mayne)

Glucose-6-phosphate dehydrogenase: a "housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress