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Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3 signaling pathway

The protective effect was even more pronounced in individuals over 50 years old, with a mortality rate of 0% in the high-lycopene group versus 71.4% in the low-lycopene group [90]

The glutathione (GSH) content was significantly restored, and the histopathological damage in the liver was also significantly improved after rhein treatment

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Glossary ALS Amyotrophic lateral sclerosis ASB1 Ankyrin repeat and SOCS box protein 1 ATP Adenosine triphosphate BAX BCL-2-associated X protein BCL-2 B-cell lymphoma 2 CBS Cystathionine -synthase CoQ/CoQ 10 Coenzyme Q/Coenzyme Q10 CoQ 10 H 2 Ubiquinol (reduced CoQ 10 ) CRC Colorectal cancer cGAS Cyclic GMPAMP synthase cGASSTING cGASstimulator of interferon genes pathway CSE Cystathionine -lyase DHODH Dihydroorotate dehydrogenase DNA Deoxyribonucleic acid Drp1 Dynamin-related protein 1 ELOB Elongin B ETC Electron transport chain ETHE1 Persulfide dioxygenase (ethylmalonic encephalopathy protein 1) FAD Flavin adenine dinucleotide FSP1 Ferroptosis suppressor protein 1 GPX4 Glutathione peroxidase 4 GSH Glutathione GSSH Glutathione persulfide GSSSG Glutathione trisulfide H 2 S Hydrogen sulfide H 2 Se Hydrogen selenide HIF-1 Hypoxia-inducible factor-1 alpha IC 50 Half-maximal inhibitory concentration IBD Inflammatory bowel disease IFN Interferon MPST/3-MST 3-Mercaptopyruvate sulfurtransferase NaHS Sodium hydrosulfide NLRP3 NLR family pyrin domain containing 3 NQO1 NAD(P)H:quinone oxidoreductase 1 NRF2 Nuclear factor erythroid 2related factor 2 PC Pyruvate carboxylase PGC1 Peroxisome proliferator-activated receptor- coactivator-1 Qred/Qox Reduced/oxidized quinone ROS Reactive oxygen species SOD/SOD2 Superoxide dismutase/Superoxide dismutase 2 SONFH Steroid-induced osteonecrosis of the femoral head SQOR Sulfide:quinone oxidoreductase STAT3 Signal transducer and activator of transcription 3 STING Stimulator of interferon genes SUOX Sulfite oxidase TST Thiosulfate sulfurtransferase UC Ulcerative colitis xCT (SLC7A11) Cystine/glutamate antiporter References 1 AbeK.KimuraH