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Direct comparison is limited because these peptides operate through entirely different mechanisms, target different tissues in research models, and have different molecular characteristics

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(Silybum marianum) (Fruit/Seeds) (Standardized to 80 mg Silymarin Flavonoids - equivalent 80%)

Mol Med Rep 10(5):22232233 Yanagisawa S, Baker JR, Vuppusetty C, Koga T, Colley T, Fenwick P, Donnelly LE, Barnes PJ, Ito K (2018) The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure