ATOX1, when bound to Cu + , can also act as a transcription factor, leading to the expression of G1/S-specific cyclin D1, inducing cell proliferation (40)
Importantly, research by Lutsenko has revealed that Atox1 promotes the synthesis of ceruloplasmin, a protein critical for iron metabolism, as well as tyrosinases (33)
And that is what we see. 2 Indeed, Loggias finding was replicated by an AFSA-funded study

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