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Therefore, a 1-week washout period was deemed sufficient to prevent carryover effects, consistent with protocols used in similar crossover designs involving acute L-carnitine supplementation

The primary causes of AKI include infections, hypovolemic shock, and associations with sepsis, medications or invasive procedures, and the long-term complications of AKI include CKD, renal failure, and cardiovascular diseases, with an increased risk of mortality (Kellum et al., 2021

doi: 10.1039/c7fo01809f 39 StephenNMJeya ShakilaRJeyasekaranGSukumarD

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Villani GR, Gallo G, Scolamiero E, Salvatore F, Ruoppolo M (2017) Classical organic acidurias: diagnosis and pathogenesis