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241,242,243,244,245,246 Similar to SLE, antibody therapies against IL-17 utilize the following two main mechanisms: direct targeting of the IL-17 pathway to inhibit inflammation and (or) indirectly inhibiting the IL-17-mediated inflammatory response by regulating Th17 cell differentiation

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2,7-Dichlorodihydrofluorescein diacetate (DCFH-DA) probe detection indicated that there was no obvious change in ROS level of A549 cells after gefitinib treatment, while in HCC827 cells, ROS level raised substantially with the incremental drug concentration (Fig