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When your liver breaks down acetaminophen, a small portion converts into NAPQI, a toxic byproduct that normally gets neutralized by glutathione

These include Stomach (gastric) cancer Duodenal cancer Esophageal cancer Ampullary cancer Structural and vascular issues Sometimes the problem isnt a sore or a tumor, but the plumbing of the digestive system itself

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Particular caution is required when using the drug There are no special precautions required

For many of these uses, high-quality human evidence and long-term safety data are limited or unavailable